Remote Ischemic Preconditioning Ameliorates Acute Kidney Injury due to Contrast Exposure in Rats through Augmented O-GlcNAcylation

<div>Azaserine decreases protein O-GlcNAcylation and blunts the renoprotection of RIPC in CI-AKI. (a, b) Immunoblots and quantitation of the global renal O-GlcNAcylation levels from rats 24 h after iohexol treatment. (c) Detection of UDP-GlcNAc concentrations in renal tissues and analysis of serum and urine biomarkers. Serum (d) and urinary (e) NGAL; SCr (f). (g, h) Photos of renal tubular injury. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Remote Ischemic Preconditioning Ameliorates Acute Kidney Injury due to Contrast Exposure in Rats through Augmented O-GlcNAcylation 