Remote Ischemic Preconditioning Ameliorates Acute Kidney Injury due to Contrast Exposure in Rats through Augmented O-GlcNAcylation

Figure 8

Schematic diagram of experimental hypothesis. RIPC increases the production of UDP-GlcNAc through the HBP, elevates the activity of OGT or inhibits the activity of OGA, increases the global O-GlcNAcylation in the kidneys, and ultimately exerts renoprotective effects under acute stress and injury.