Research Article

Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes

Figure 8

A proposed mechanism of action of gossypol (GSP) in glucose homeostasis through IRS-1/Akt signaling cascade activation and gluconeogenesis repression.