A Novel Small Peptide Inhibitor of NFκB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer

Figure 4

RH10 effects in combination with other therapies. KAT-4 cells were pretreated with 1 ng/ml RH10. Cell proliferation was evaluated after 24 hours of treatment with cisplatin (a), doxorubicin (b), or ionizing radiation (c). (a) RH10 further reduce cell proliferation in response to cisplatin ( vs. CTRL, vs. cisplatin, ! vs. RH10). Data are reported as mean ± SD. (b) RH10 further reduce cell proliferation in response to doxorubicin ( vs. CTRL, vs. doxorubicin, ! vs. RH10). Data are reported as mean ± SD. (c) RH10 further reduce cell proliferation in response to ionizing radiation ( vs. CTRL, vs. ionizing radiation, ! vs. RH10). Data are reported as mean ± SD.

(a)

(b)

(c)