Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

Figure 6

Antiestrogenic effects of 8 natural products in the ERα transactivation assay using MCF-7 cells transiently transfected with pERE-TATA-Luc. Cells were treated with the tested chemicals at a series of concentrations. The values represent the mean ± SD of three independent experiments and are presented as the percentage of the response, with the control defined as 100%. , , and .

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