Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals

Table 1

Characteristics of the experimental animal at 22 weeks old.

	Obese ()	Lean ()	value
Body weight (g)	559 ± 28	410 ± 30	<0.001
Fat mass (g)	213 ± 11	24 ± 6	<0.001
Free fat mass (g)	261 ± 49	303 ± 19	0.021
MDA (μM)	1.75 ± 0.64	0.61 ± 0.19	0.001
TAC (mM Trolox)	436 ± 191	265 ± 40	0.020

Data are represented as the mean ± standard error of the mean (SEM). value shows statistically significant differences compared with the control-lean group. MDA: malondialdehyde; TAC: total antioxidant capacity.