Impaired Mitophagy of Nucleated Erythroid Cells Leads to Anemia in Patients with Myelodysplastic Syndromes

Figure 3

The mRNA expression of the autophagy regulator gene in GlycoA⁺ NRBC measured by Q-PCR. (a) The AMPK mRNA expression in GlycoA⁺ NRBC of high-risk MDS was lower than that in controls and low-risk MDS. (b) The ULK1 mRNA expression in GlycoA⁺ NRBC of high-risk MDS was lower than that in controls and low-risk MDS. (c) The mTOR mRNA expression in GlycoA⁺ NRBC of high-risk MDS was higher than that in controls and low-risk MDS (, ).

(a)

(b)

(c)