β3-Adrenoreceptors Control Mitochondrial Dormancy in Melanoma and Embryonic Stem Cells

Figure 4

Functional β3-AR in mitochondria: a new receptor for an old compartment. WB analysis of β3-AR on mitochondria proteins (a). Confocal representative images of β3-ARs, MitoTracker, and merge of both markers (b). ATP production measured on isolated mitochondria as in Figure 1(d). Ectopic ADP was added to the reaction mix (c). mtROS measured as in Figure 3(a) (d). Summary scheme of the study (e). Data are representative of at least three experiments (mean and SD). values for SR59230A treatment: ; values for genipin treatment: .