Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways

Figure 2

Andro attenuated hepatic inflammation in mice induced by CCl₄. (a) Representative histology of H&E and immunohistochemical staining of CD68. (b) Quantification of CD68-positive staining areas was measured by ImageJ software. (c) The protein expression of CD68 was examined by Western blot. (d–f) The mRNA levels of IL-1β, IL-6, and MCP-1 were measured by q-PCR. . and versus control mice. , , and versus mice induced by CCl₄.

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