Computational Studies Applied to Flavonoids against Alzheimer’s and Parkinson’s Diseases

Table 3

Description of energy scores of flavonoids and control compounds on PD target proteins.

Flavonoids	Aden A2A	α-Synuclein	COMT	MAO-B
3-O-methylquercetin	−71.095	−74.901	−53.659	−140.763
8-prenylnaringenin	−83.692	−83.012	−67.998	−145.425
Afzelechin	−61.973	−70.911	−51.278	−107.22
Ampelopsin	−60.848	−74.188	−53.806	−134.626
Aromadendrin	−53.880	−66.701	−45.951	−123.726
Aspalathin	−55.009	−86.361	−56.396	−150.386
Aurantinidin	−67.749	−75.414	−56.591	−117.977
Butin	−68.355	−77.949	−60.034	−124.25
Capensinidin	−84.669	−87.321	−71.529	−140.926
Chrysin	−59.594	−70.872	−52.576	−120.287
Delphinidin	−70.457	−82.877	−68.376	−126.481
Di-hydrogossypetin	−56.359	−73.612	−48.949	−135.483
Di-hydromorin	−61.416	−66.071	−54.329	−131.088
Epicatechin	−66.996	−74.661	−53.054	−122.78
Eriodictyol	−66.790	−74.167	−55.545	−119.801
Europinidin	−75.421	−79.694	−74.993	−140.585
Fisetin	−67.182	−79.763	−64.252	−130.773
Fisetinidol	−64.279	−72.271	−59.406	−118.506
Fustin	−59.854	−76.510	−56.851	−135.63
Epicatechin gallate	−113.727	−98.330	−96.205	−174.333
Genistein	−68.316	−73.585	−58.867	−119.162
Gossypetin	−63.019	−75.620	−58.446	−139.059
Hesperidin	−101.446	−89.698	−65.656	−181.222
Hibiscetin	−71.879	−75.302	−60.718	−137.019
Homoeriodictyol	−75.599	−82.786	−62.698	−141.639
Isosakuranetin	−65.924	−71.351	−49.177	−131.514
Luteolinidin	−65.240	−80.031	−57.149	−122.481
Meciadanol	−73.596	−77.668	−55.342	−126.337
Mesquitol	−60.219	−74.776	−51.753	−128.058
Morin	−70.744	−84.587	−59.595	−139.778
Norartocarpetin	−67.527	−77.898	−60.514	−137.774
Pinocembrin	−56.707	−66.573	−46.254	−113.423
Procyanidin	−98.216	−130.002	−85.226	−88.460
Rhamnetin	−69.702	−83.582	−49.586	−142.785
Robinetinidol	−62.594	−78.967	−51.172	−125.203
Rosinidin	−83.735	−95.587	−63.376	−149.196
Sakuranetin	−70.695	−74.984	−51.408	−129.56
Sterubin	−69.560	−77.022	−56.015	−141.623
Taxifolin	−56.665	−69.743	−52.804	−126.612