p-Coumaric Acid Protects Human Lens Epithelial Cells against Oxidative Stress-Induced Apoptosis by MAPK Signaling

Figure 1

Effects of p-CA on cell viability of H₂O₂-induced cell death in HLE cells. (a) Structure of p-CA. (b) HLE cells were treated with a series of H₂O₂ concentrations (0–300 μM) for 24 h. (c) HLE cells were incubated with different concentrations of p-CA (0–100 μM) for 24 h. (d) HLE cells are preincubated with p-CA (0–100 μM) for 2 h before 275 μM H₂O₂ treated for 24 h. Cell viability was measured using the MTT method. Data are expressed as the mean ± SEM (). , compared with the untreated control group; , and , compared with the H₂O₂-treated group.

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