Research Article

The Protective Effect of the Total Flavonoids of Abelmoschus esculentus L. Flowers on Transient Cerebral Ischemia-Reperfusion Injury Is due to Activation of the Nrf2-ARE Pathway

Figure 8

Mechanism of TCI-RI and protective effect of AFF on TCI-RI in nerve cells. AFF directly scavenged free radicals and indirectly activated the Nrf2-ARE pathway to enhance the expressions of antioxidase NQO1 and HO-1 and increase SOD content, against oxidative stress, which significantly reduced the content of NO, MDA, and protected TCI-RI.