SIRT1 Activity in Peripheral Blood Mononuclear Cells Correlates with Altered Lung Function in Patients with Chronic Obstructive Pulmonary Disease

Table 1

Main characteristics of the study population.

	HnS	HS	COPD	value
Age, yr	66.05 ± 3.66	66.20 ± 4.98	68.58 ± 6.27	0.136
Sex ratio (M/F)	11/9	11/9	18/7	0.975
BMI, kg/m^2	25.75 ± 2.54	23.01 ± 4.49	26.90 ± 5.99	0.071
FEV1, (% pred.)	110.10 ± 12.84	106.07 ± 11.24	53.96 ± 9.50	<0.0001
FEV1/FVC, %	80.62 ± 5.02	80.92 ± 6.01	54.10 ± 7.88^§	<0.0001
Pack/years	—	21.53 ± 12.08	52.34 ± 39.88	0.002

Data are expressed as mean ± SD. HnS: healthy nonsmokers; HS: healthy smokers; COPD: chronic obstructive pulmonary disease; BMI: body mass index; FEV1 (% pred.): forced expiratory volume in 1 second; FVC: forced vital capacity. COPD versus HnS, ; COPD versus HS, .