Neuroprotective Effect of Caryocar brasiliense Camb. Leaves Is Associated with Anticholinesterase and Antioxidant Properties

Figure 6

Effect of CHE treatment on locomotor activity (a, b) and memory (c, d) of mice subjected to 90 days of aluminium exposure. (a) Number of crossings of mice groups as evaluated in the open-field test. (b) Time (s) to climb backwards out of the tube within 30 sec for the examined animals in the chimney test. Latencies of retention time (s) in mice as evaluated in the step-down test at 90 min (c) and 24 h (d) after shock challenge. Each column represents mean ± SEM of 10 animals. (, , and in comparison to group III). I: control group; II: quercetin 30 mg/kg; III: aluminium group; IV: CHE 10 mg/kg; V: CHE 100 mg/kg; VI: CHE 300 mg/kg.

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