Research Article

Neuroprotective Effect of Caryocar brasiliense Camb. Leaves Is Associated with Anticholinesterase and Antioxidant Properties

Figure 9

Histological sections of the frontal cerebral cortex stained by hematoxylin-eosin method. I: control group; II: quercetin 30 mg/kg; III: aluminium group; IV: CHE 10 mg/kg; V: CHE 100 mg/kg; VI: CHE 300 mg/kg. All aluminium-exposed groups presented shrunken neurons with cytoplasm being intensely eosinophilic (arrows). These necrotic neurons presented pyknotic nucleus with no discernible nucleolus. In the graphs, each column represents mean ± SEM of 3 animals per group. (, , and in comparison to group III).