1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation

Figure 6

TaClo negatively affected dopaminergic neurons. A schematic diagram showing that TaClo induces the demyelination and apoptosis of dopaminergic neurons by causing mitochondrial dysfunction and triggering the innate immune response in the nigrostriatal system.