miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice

Figure 4

miR-200a reduced oxidative stress in DOX-treated mice: (a) the level of MMP2 and MMP9 in the hearts (); (b) the level of TNF-α and IL-6 in the hearts (); (c, d) the levels of GSH and cardiac MDA in the hearts (); (e) the level of 4-HNE in the hearts (); (f) the level of SOD2 mRNA in the hearts (); (g) protein expression of Nrf2 and HO-1 (). compared with the group with saline. ^# compared with mice after DOX injection.

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