Label-Free Proteomics of the Fetal Pancreas Identifies Deficits in the Peroxisome in Rats with Intrauterine Growth Restriction

Figure 9

Cell cycle regulators and Hdacs. (a, b) Representative immunoblotting and densitometric quantification of cell cycle regulators in the fetal pancreas. (c, d) Representative immunoblotting and densitometry analysis of Hdacs in the fetal pancreas. Results were expressed as the . , vs. control. (e) The mRNA levels of these proteins in the fetal pancreas were determined by quantitative RT-PCR with β-actin as the reference gene ( per group, , vs. control). (f) The STRING networks of cell cycle regulators and Hdacs with altered expression. Colored lines between the proteins indicate the various types of interaction evidence.

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