Metformin Activates the Protective Effects of the AMPK Pathway in Acute Lung Injury Caused by Paraquat Poisoning

Figure 1

Effect of MET on the W/D ratio of lung tissue in rats treated with PQ. The PQ group received a single intraperitoneal injection of 30 mg/kg paraquat, while the control group received an intraperitoneal injection of the same volume of normal saline, and the MET and PQ+MET groups received intragastric treatment with 400 mg/kg MET (once per day for 7 days) 2 hours after model establishment. After one night of fasting, the lungs of the rats were removed, and the W/D ratio was calculated. Data are shown as the ( except for the PQ group () and the PQ+MET group ()); , ; vs. control group, vs. PQ group.