5<i>α</i>,6<i>α</i>-Epoxyphytosterols and 5<i>α</i>,6<i>α</i>-Epoxycholesterol Increase Oxidative Stress in Rats on Low-Cholesterol Diet

<div>Anti-7-ketocholesterol (anti-7-ketoCH) antibody levels (<svg height="9.65783pt" id="M38" style="vertical-align:-0.3499298pt" version="1.1" viewbox="-0.0498162 -9.3079 168.777 9.65783" width="168.777pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M797 0V26C739 32 732 36 732 103V296C732 394 682 449 605 449C576 449 550 437 529 423C504 407 475 389 446 366C425 418 382 449 334 449C303 449 279 437 253 421C222 403 201 385 180 371V452C135 432 85 419 41 411V388C99 379 102 374 102 310V103C102 38 93 32 27 26V0H238V26C189 32 180 38 180 103V338C210 363 250 390 289 390C351 390 377 348 377 275V103C377 37 368 32 306 26V0H520V26C465 32 456 38 456 101V296C456 314 455 326 453 338C491 369 529 390 565 390C628 390 653 345 653 274V107C653 36 642 32 583 26V0H797Z"></path></g><g transform="matrix(.013,0,0,-0.013,10.595,0)"><path d="M380 106C343 72 306 56 265 56C195 56 116 112 115 248C235 252 361 262 377 265C396 269 400 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transform="matrix(.013,0,0,-0.013,151.398,0)"><path d="M135 536C164 536 186 560 186 587C186 617 164 639 136 639C109 639 85 617 85 587C85 560 109 536 135 536ZM252 0V26C188 32 181 38 181 106V451C138 433 90 420 39 412V388C99 379 102 374 102 312V106C102 38 95 32 32 26V0H252Z"></path></g><g transform="matrix(.013,0,0,-0.013,154.882,0)"><path d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"></path></g><g transform="matrix(.013,0,0,-0.013,161.355,0)"><path d="M524 0V26C466 32 460 36 460 104V297C460 393 411 449 331 449C302 449 276 437 248 419C223 402 201 387 181 372V451C137 432 90 420 42 411V388C96 378 102 374 102 310V104C102 38 97 33 29 26V0H246V26C187 32 181 36 181 104V339C211 365 250 390 290 390C357 390 381 345 381 276V109C381 40 374 32 315 26V0H524Z"></path></g></svg> (SD)) in the serum of rats exposed to 5<i>α</i>,6<i>α</i>-epoxycholesterol (ECh group) and 5<i>α</i>,6<i>α</i>-epoxyphytosterols (ES group) vs controls (C).</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: 5<i>α</i>,6<i>α</i>-Epoxyphytosterols and 5<i>α</i>,6<i>α</i>-Epoxycholesterol Increase Oxidative Stress in Rats on Low-Cholesterol Diet 

Oxidative Medicine and Cellular Longevity

5α,6α-Epoxyphytosterols and 5α,6α-Epoxycholesterol Increase Oxidative Stress in Rats on Low-Cholesterol Diet

Figure 2