TNFα-Mediated Necroptosis Aggravates Ischemia-Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response

Figure 6

Inhibition of necroptosis reduces ROS after IRI of NAFLD both in vivo and in vitro. (a) Representative images of DHE staining of liver sections in CD- and HFD-fed mice with Nec-1 and GSK872 pretreatment. Scale bars, 100 μm. (b) Representative images of DE-FHDA staining of hepatocytes with Nec-1 and GSK872 pretreatment followed by TNFα stimulation. Scale bars, 100 μm.

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