Research Article
Sitagliptin-Dependent Differences in the Intensity of Oxidative Stress in Rat Livers Subjected to Ischemia and Reperfusion
Figure 4
Histopathological examination of liver tissue. Histological examination (stained with hematoxylin-eosin, magnification ×400, bar 50 μm) from group C, rats nontreated and nonsubjected to IR (a); group CIR, rats nontreated and subjected to IR (b); group S, rats treated with STG and not subjected to IR (c); and from group SIR, rats treated with STG and subjected to IR (d). No significant differences in the hepatic structure were seen in both ischemic and nonischemic groups of rats. In drug-treated groups, the percentage of steatosis was statistically higher than that in nontreated groups (CIR vs. SIR, , and C vs. S, ).
(a) |
(b) |
(c) |
(d) |