Research Article

SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway

Figure 5

SIRT7 regulates proinflammatory cytokines in LPS-treated DCMECs. (a, b) After transfection for 48 h, DCMECs were treated with LPS for 6 h. The levels of TNF-α, IL-1β, and IL-6 mRNA were determined by qRT-PCR. (c) The protein levels of IL-1β and IL-6 were determined via western blotting. (d) The levels of IL-1β and IL-6 in the cell medium were detected by ELISA. Data are expressed as , , and .
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