FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX

Figure 7

FOXO1 protects against apoptosis in HK-2 cells under high glucose via regulating TXNIP-TRX. (a–h) Apoptosis was measured by flow cytometry, using FITC-annexin V and propidium iodide as markers. Data are presented as (). vs. normal glucose (NG); vs. high glucose (HG); vs. FOXO1 knockin (KI); vs. FOXO1 knockout (KO).

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