Uric Acid Provides Protective Role in Red Blood Cells by Antioxidant Defense: A Hypothetical Analysis

Table 3

Comparison of red blood cell parameters in male and female subjects, stratified according to the level of UA.

	Low UA	Normal UA	High UA	value	value
Male
Age (years)				27.711	<0.001^a,b,c
BMI (kg/m^2)				0.536	0.585
MCH (pg)				0.204	0.815
MCHC (g/l)				17.101	<0.001^a,b,c
MCV (fl)				9.523	<0.001^a,b,c
RDW (%)				2.998	0.049^a
RBC (10^12/l)				129.763	<0.001^a,b,c
Hemoglobin (g/l)				143.954	<0.001^a,b,c
UA (mmol/l)				5897.909	<0.001^a,b,c
Cr (mmol/l)				4.844	0.008^b
UA/Cr ratio				108.731	<0.001^a,b,c
Female
Age (years)				51.531	<0.001^a,c
BMI (kg/m^2)				0.390	0.677
MCH (pg)				2.987	0.051
MCHC (g/l)				0.235	0.791
MCV (fl)				5.335	0.005^b,c
RDW (%)				4.586	0.010^c
RBC (10^12/l)				24.123	<0.001^a,b,c
Hemoglobin (g/l)				16.390	<0.001^a,b,c
UA (mmol/l)				2848.194	<0.001^a,b,c
Cr (mmol/l)				12.774	<0.001^a,c
UA/Cr ratio				646.919	<0.001^a,b,c

RDW: red blood cell distribution width; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; MCV: mean corpuscular volume; RBC: red blood cell count; Cr: creatinine; UA: uric acid; BMI: body mass index. Low UA: male ( mmol/l), female ( mmol/l); normal UA: male ( mmol/l), female ( mmol/l); high UA: male ( mmol/l), female ( mmol/l). ^a for the difference between low and normal (1-way ANOVA with the LSD post hoc test). ^b for the difference between low and high (1-way ANOVA with the LSD post hoc test). ^c for the difference between normal and high (1-way ANOVA with the LSD post hoc test).