Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro

Figure 7

TLR4 deficiency attenuates H/R-induced hepatocyte apoptosis and downstream molecule activation. (a, b) Western blot-assisted analysis of Bcl-2, Bax, C-caspase 3, and β-actin. (c, d) Western blot-assisted analysis of TLR4, FADD, MyD88, TRAF6, p-IKKα/β, p-NF-κB p65, NF-κB p65, and GAPDH. Values represent deviation (SD) values (). , versus the control group; ^#, ^## versus the H/R group; ^&, ^&& versus the H/R+AL group;^@, ^@@ versus the H/R+siTLR4 group; one-way ANOVA with Tukey test.

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