Research Article

Prevention of Huntington’s Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress

Table 1

Effect of tolfenamic acid on locomotor behavior in R6/1 mice.

GroupExploration distance (mm)Movement speed (mm/s)Exploration numberResting time (s)Exploration time (s)

Control
Modelaaaa
TA 25 mg/kgbbbb
TA 50 mg/kgcccc

All of the results are expressed as the . or 8. vs. the control group; and vs. the model group.