Research Article

Prevention of Huntington’s Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress

Table 3

Effect of tolfenamic acid on oxidative damage (glutathione levels) in the brain of R6/1 mice.

GroupTotal glutathione (μmol/L)Oxidized glutathione (μmol/L)Reduced glutathione (μmol/L)

Control
Modelaa
TA 25 mg/kgbb
TA 50 mg/kgbb

All of the results are expressed as the . . vs. the control group; vs. the model group.