Dose-Dependent Behavioral and Antioxidant Effects of Quercetin and Methanolic and Acetonic Extracts from Heterotheca inuloides on Several Rat Tissues following Kainic Acid-Induced Status Epilepticus

Figures 3

Effects of methanolic extract on the activity of the antioxidant enzymes GPx, GR, CAT, and SOD in the cerebellum (A), prefrontal cortex (B), cerebral hemispheres (C), and medulla (D) of Wistar rats during KA-induced injury. The results were analyzed by one-way analysis of variance (ANOVA), and Bonferroni’s multiple comparisons test was used to compare the outcomes between the experimental and respective control groups (KA only, black bar). For GPx: ^xxx in the extracts and quercetin in all its doses and in all brain tissues except in the ME30+KA group in the cerebral hemispheres vs. KA, ^xx in the ME30+KA in the cerebral hemispheres vs. KA; for GR, CAT, and SOD: ^xxx in the extracts and quercetin in all its doses and in all brain tissues. Each determination was performed in triplicate, and the data are expressed as the ( per group). ns: not significant.