Research Article

Dose-Dependent Behavioral and Antioxidant Effects of Quercetin and Methanolic and Acetonic Extracts from Heterotheca inuloides on Several Rat Tissues following Kainic Acid-Induced Status Epilepticus

Table 2

Percentage (%) of decrease in TBARS concentration in the cerebellum, prefrontal cortex, cerebral hemispheres, and medulla, in the treatment groups (methanolic extract, acetonic extract, and quercetin coadministered with KA).

TreatmentTreated (KA) cerebellum decrease (%)Treated (KA) cortex decrease (%)Treated (KA) cerebral hemisphere decrease (%)Treated (KA) medulla decrease (%)

Methanolic extract
 30 mg/kg52.5848.0055.1357.44
 100 mg/kg64.4654.0061.0067.27
 300 mg/kg77.0969.0073.0077.00
Acetonic extract
 30 mg/kg53.5348.0052.0050.00
 100 mg/kg61.6252.4860.4059.00
 300 mg/kg67.2253.4665.0064.43
Quercetin
 30 mg/kg55.1958.1458.0357.00
 100 mg/kg67.0066.0071.5465.29
 300 mg/kg10082.3682.34100