Dose-Dependent Behavioral and Antioxidant Effects of Quercetin and Methanolic and Acetonic Extracts from Heterotheca inuloides on Several Rat Tissues following Kainic Acid-Induced Status Epilepticus

Table 4

Percentage (%) of decrease in CP concentration in the cerebellum, prefrontal cortex, cerebral hemispheres, and medulla, in the treatment groups (methanolic extract, acetonic extract, and quercetin coadministered with KA).

Treatment	Treated (KA) cerebellum decrease (%)	Treated (KA) cortex decrease (%)	Treated (KA) cerebral hemisphere decrease (%)	Treated (KA) medulla decrease (%)
Methanolic extract
30 mg/kg	39.42	41.40	55.00	36.36
100 mg/kg	38.34	33.27	47.00	31.27
300 mg/kg	38.78	32.85	47.00	31.00
Acetonic extract
30 mg/kg	49.74	43.04	66.00	43.00
100 mg/kg	47.24	39.01	46.00	35.50
300 mg/kg	48.49	34.62	39.51	34.00
Quercetin
30 mg/kg	25.00	29.65	32.27	27.00
100 mg/kg	23.16	24.40	24.69	26.18
300 mg/kg	18.00	24.11	20.41	24.15