Dose-Dependent Behavioral and Antioxidant Effects of Quercetin and Methanolic and Acetonic Extracts from Heterotheca inuloides on Several Rat Tissues following Kainic Acid-Induced Status Epilepticus

Table 6

Percentage (%) of increase in GPx, GR, CAT, and SOD activities in the cerebral hemispheres and medulla in the treatment groups (methanolic extract, acetonic extract, and quercetin treated with KA).

Treatment	Treated (KA) GPx	Treated (KA) GR	Treated (KA) CAT	Treated (KA) SOD	Treated (KA) GPx	Treated (KA) GR	Treated (KA) CAT	Treated (KA) SOD
Tissue	Cerebral hemispheres (% increase)				Medulla (% increase)
Methanolic extract
30 mg/kg	39.00	31.30	69.04	43.07	30.47	40.00	57.00	28.39
100 mg/kg	51.31	48.02	77.00	46.44	39.00	48.13	60.00	39.19
300 mg/kg	70.11	64.00	81.21	60.44	58.00	57.07	67.14	48.02
Acetonic extract
30 mg/kg	68.14	45.14	53.41	65.24	47.45	59.13	45.54	60.63
100 mg/kg	71.40	57.06	59.77	73.39	60.08	67.77	48.99	69.25
300 mg/kg	72.85	64.64	67.91	76.73	64.74	70.13	62.37	75.12
Quercetin
30 mg/kg	61.00	52.23	31.00	51.08	43.00	49.06	30.15	59.41
100 mg/kg	70.00	61.00	40.47	65.00	47.46	54.28	48.21	71.00
300 mg/kg	69.03	67.21	48.00	70.21	69.03	62.00	63.22	76.00