Internalization and Transportation of Endothelial Cell Surface K<sub>Ca</sub>2.3 and K<sub>Ca</sub>3.1 in Normal Pregnancy and Preeclampsia

<div>Membrane levels of K<sub>Ca</sub>2.3 and K<sub>Ca</sub>3.1 are altered in NP and PE. (a) PM levels of K<sub>Ca</sub>2.3 and K<sub>Ca</sub>3.1 in ECs treated with NNP or NP serum. (b) PM levels of K<sub>Ca</sub>2.3 and K<sub>Ca</sub>3.1 in ECs treated with NP or PE serum. (c, d) PM levels of K<sub>Ca</sub>2.3 (c) and K<sub>Ca</sub>3.1 (d) in ECs treated with CM, NNP serum, NP serum, or PE serum. (e) PM levels of K<sub>Ca</sub>2.3 or K<sub>Ca</sub>3.1 in ECs treated with oxidized LDL. Reduced K<sub>Ca</sub>2.3 or K<sub>Ca</sub>3.1 levels were reversed by blocking oxidized LDL receptor using an anti-LOX1 Ab. Blots shown are representative of the three to five experiments performed with three to five different cultures. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Internalization and Transportation of Endothelial Cell Surface K<sub>Ca</sub>2.3 and K<sub>Ca</sub>3.1 in Normal Pregnancy and Preeclampsia 

Oxidative Medicine and Cellular Longevity

Internalization and Transportation of Endothelial Cell Surface KCa2.3 and KCa3.1 in Normal Pregnancy and Preeclampsia

Figure 1

Internalization and Transportation of Endothelial Cell Surface K_Ca2.3 and K_Ca3.1 in Normal Pregnancy and Preeclampsia