Carnosol Improved Lifespan and Healthspan by Promoting Antioxidant Capacity in Caenorhabditis elegans

Table 2

Statistical analysis of the paralysis time of C. elegans.

Genotype	Treatment^1	Mean time^2	Median time^3	Maximum time^4	% effect^5	value^6	Uncensored/
CL4176	0 μM (25°C)	^a	^a	^a	—	—	180/180
	180 μM (25°C)	^b	^b	^b	21	<0.0001	180/180
AM140	0 μM	^a	^a	^a	—	—	155/180
	180 μM	^b	^b	^b	14	<0.0001	139/180

¹The control groups for paralysis assays were referred to previously published data [12]. ², where is the age category, is the number of worms that paralyzed in the age interval , and is the total number of worms. ³The median paralysis is the time at which the percentage of nonparalytic worms equals 50%. ⁴The maximum paralysis is the time at which paralysis equals 0%. ⁵% effect was calculated by , where is the mean paralysis time of worms treated with carnosol and is the mean paralysis time of control. ⁶The value was calculated using the log-rank test by comparing the carnosol-treated group with the control.