Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells

Figure 1

Stretch-induced apoptosis of endothelial cells (ECs). (a) Apoptosis of ECs under nonstretch, 15% stretch, and 20% stretch conditions were measured by TUNEL assay. TUNEL-positive cells were stained into green, while nuclei were counterstained into blue. (b) Proteins associated with proapoptosis and antiapoptosis were detected by Western blot. The target protein was normalized to that of β-actin.

(a)

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