LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss

Figure 2

Differentially expressed lncRNAs in the cochlea of aged C57BL/6 mice. (a) Volcano plot showing comparative cochlea lncRNA gene expression in 4-week (young)- and 12-month (old)-old C57BL/6 mice (). Red dots indicated the significantly increased transcripts (88), and blue dots represented the significantly decreased transcripts (46) in old mice (). (b) Heat map showing hierarchical clustering of differentially expressed lncRNAs. Red indicated high relative expression, and blue represented low relative expression. (c) RT-qPCR analysis validation of 6 differentially expressed lncRNAs. , .

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