“Redox Imaging” to Distinguish Cells with Different Proliferative Indexes: Superoxide, Hydroperoxides, and Their Ratio as Potential Biomarkers

Figure 1

Structural formulas of nitroxide probes used in our study and potential mechanism of their redox transformations in living cells and tissues. Mito-TEMPO and methoxy-TEMPO, which penetrate the cells, allow the analysis of the intracellular redox capacity, while carboxy-PROXYL, which does not penetrate the cells, allows the analysis of the extracellular redox capacity (according to Soule et al. [13]).