Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury

Figure 4

Cardiac-specific ATGL overexpression prevents lipid accumulation following burn injury. (a) Identification of WT and MHC-ATGL Het mice by PCR analysis. (b, c) Immunoblot analysis showing ATGL expression in WT and MHC-ATGL Het mice under basal conditions; . (d, e) Analysis comparing serum TG and FFA between WT and MHC-ATGL Het mice with or without burn injury; . (f, g) Cardiac TG and FFA were compared between WT and MHC-ATGL Het mice with or without burn stimulation; . MHC-ATGL denotes MHC-ATGL Het. Data are shown as the . , , and . values were derived from two-tailed Student’s -test (c) and one-way ANOVA with the appropriate posttest (d–g).

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