A Metabonomics Investigation into the Therapeutic Effects of BuChang NaoXinTong Capsules on Reversing the Amino Acid-Protein Interaction Network of Cerebral Ischemia

Table 2

Linear range and correlation coefficient and sensitivity of 10 amino acids in ESI⁺ mode.

Amino acids	Linear range (ng/mL)	r	LOD			LOQ
			Content	S/N average	RSD% ()	Content	S/N average	RSD% ()
Tryptophan	6.04-386.25	0.9985	100 pg/mL	5.27	9.67	1000 pg/mL	14.58	10.89
Tyrosine	2.50-160.00	0.9844	15 pg/mL	4.10	14.37	150 pg/mL	12.61	11.71
Phenylalanine	0.98-62.40	0.9995	2 pg/mL	12.02	12.53	20 pg/mL	13.18	16.91
Glutamate	37.19-2380.00	0.9995	50 pg/mL	6.44	13.31	500 pg/mL	14.83	12.77
Glutamine	177.19-11340.00	0.9834	5 pg/mL	4.64	19.54	50 pg/mL	17.72	10.14
Isoleucine	1.23-78.60	0.9960	3.5 pg/mL	5.04	15.19	35 pg/mL	12.97	5.13
Leucine	0.90-57.50	0.9995	0.7 pg/mL	6.57	16.79	7 pg/mL	14.30	12.86
Taurine	43.24-2767.50	0.9980	110 pg/mL	3.16	13.19	1100 pg/mL	17.05	14.49
Valine	1.58-101.00	0.9995	3.5 pg/mL	4.65	12.14	35 pg/mL	10.95	9.52
Alanine	18.28-1170.00	0.9995	100 pg/mL	5.35	14.55	1000 pg/mL	12.69	15.76

S/N was calculated as RMS (root mean square) S/N.