Oxidized Low-Density Lipoprotein (Ox-LDL) and Triggering Receptor-Expressed Myeloid Cell (TREM-1) Levels Are Associated with Cardiometabolic Risk in Nonobese, Clinically Healthy, and Young Adults

Figure 1

Markers of oxidative stress (Ox-LDL) and inflammation (sTREM-1) and other variables of interest related to the components of the CMR among individuals with waist circumference above and below the recommendation. (a) The heat map was assessed by unsupervised bidirectional hierarchical cluster analysis (Ward’s method) and normalized by Zscore of individuals categorized by waist circumference above or below the profile recommendation. Differences in marker levels between above compared to below by of the Student -test was considered significant with a value < 0.05 and statistically significant differences were highlighted in black. Fold changes were calculated and statistically significant differences are highlighted in black. (b) Biochemistry and inflammatory parameters that displayed statistically significant differences between the waist circumference tested by Mann–Whitney test. BMI: body mass index; WC: waist circumference; Per fat: percentage fat; TG: triacylglycerol; HDL-c: high-density lipoprotein; LDL-c: low-density lipoprotein; VLDL-c: very low-density lipoprotein; DBP: diastolic blood pressure; SPB: systolic blood pressure; TC HDL: atherogenic cholesterol; Ox-LDL: oxidized low-density lipoprotein; sTREM-1: soluble triggering receptor-expressed myeloid cells-1.

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