Research Article

Resumption of Autophagy by Ubisol-Q10 in Presenilin-1 Mutated Fibroblasts and Transgenic AD Mice: Implications for Inhibition of Senescence and Neuroprotection

Figure 2

Ubisol-Q10-treated PSAF incubated with SP600125 JNK1 inhibitor showed a resumption of premature senescence bringing fibroblasts back to the original AD morphology. Cells were incubated in senescence-associated beta-galactosidase to identify senescent fibroblasts. Micrographs were taken at 200x. .