Research Article

N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells

Figure 2

ROS levels and cell viability and JNK protein expression and activity in H9c2 cells following different durations of hypoxia and a 1-hour period of reperfusion. (a) ROS level measured by flow cytometry; . Data are expressed as the base of the levels of the control group. (b) Cell viability determined by the MTT assay; . Data are expressed as the base of the levels of the control group. (c) JNK and p-JNK protein levels as assessed by Western blot; . All values are represented as . vs. control group; # vs. H: 1 hour/R: 1 hour group; vs. H: 2 hours/R: 1 hour group.
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