Research Article
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells
Figure 3
Effects of JNK on Sab protein and Src protein expression and the ROS level in mitochondria in H9c2 cells. (a) p-JNK, Sab, p-Src, c-Src, and COX-IV levels were analyzed by Western blot; . Data are expressed as the base of the levels of the H/R group. (b) The level of mitochondrial ROS was detected by the laser scanning confocal microscope, and the mean fluorescence intensity was measured by the Image-Pro Plus software; . Data are expressed as the base of the levels of the control group. All values are expressed as . vs. control group; # vs. H/R group (×400, μm).
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