Aspirin Eugenol Ester Reduces H₂O₂-Induced Oxidative Stress of HUVECs via Mitochondria-Lysosome Axis

Figure 6

Genetic inhibition of Bcl2 reduced the effect of AEE on H₂O₂-induced mitochondrial and lysosomal dysfunction. (a, b) The changes in the mitochondrial membrane potential between different treatment groups ((a) power). (c, d) The changes in ROS production between different treatment groups ((c) power). (e, f) The changes in CTSD and Cas3 activity among different treatment groups. “+” with the treatment in the HUVECs; “-” without the treatment in the HUVECs. Values are expressed as , ; , compared with the group of overexpression alone; ^#, compared with the group of H₂O₂ alone (one-way ANOVA followed with Duncan’s multiple comparisons).

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