Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer’s Disease

Table 2

The proposed identity of main significantly decreased metabolites in modified-HLJDD solution as compared with HLJDD solution ( and ).

No.	Rt (sec)		Scan mode	Proposed identity	Fold change
1	41.926	255.2318365	ESI-	Palmitic acid	0.025
2	104.5675	303.0493473	ESI-	Taxifolin	0.027
3	40.3525	331.0809904	ESI+	Baicalein	0.035
4	204.4315	549.1595046	ESI+	Puerarin xyloside	0.036
5	204.029	547.1436023	ESI-	Puerarin xyloside	0.055
6	44.7035	301.034413	ESI-	Quercetin	0.04
7	41.5445	301.0704952	ESI+	Diosmetin	0.04
8	93.245	351.017593	ESI-	Glycitein	0.04
9	179.129	283.0598699	ESI-	Glycitein	0.07
10	35.1845	345.0968707	ESI+	Prunetin	0.047
11	40.656	283.2638094	ESI-	Wogonin	0.055
12	220.9455	447.0925415	ESI+	Baicalin	0.06
13	78.325	269.0918269	ESI+	Inosine	0.06
14	213.5715	355.0439436	ESI-	Phenolphthalein	0.089
15	44.9385	287.0909411	ESI+	4,5-Dihydroxy-7-methoxyflavanone	0.097
16	145.5845	417.1185387	ESI+	Daidzin	0.10
17	245.733	463.0857816	ESI-	Isoquercitin	0.13
18	177.391	253.0495934	ESI-	Chrysin	0.16
19	113.6665	433.1474268	ESI+	Indolelactic acid	0.18
20	42.905	271.0599859	ESI+	Apigenin	0.19
21	91.8115	433.1133567	ESI+	Apigenin 7-glucoside	0.20
22	41.536	359.1128039	ESI+	Berberine	0.24
23	36.886	286.0792349	ESI+	Flavone	0.28
24	102.493	215.0338159	ESI-	3-Chloro-L-tyrosine	0.33
25	406.4715	323.0268477	ESI-	Uridine 5-monophosphate (UMP)	0.55
26	26.0535	167.037797	ESI-	Homogentisic acid	0.70
27	396.7205	348.0703451	ESI+	Adenosine monophosphate (AMP)	0.63
28	395.9115	387.0914333	ESI-	Adenosine monophosphate (AMP)	0.77

and .