Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

<div>The effects of HNK on neuronal apoptosis in the hippocampal CA1 and DG regions of mice induced by surgery/sevoflurane. (a, b) The representative images showing TUNEL staining in the hippocampal CA1 and DG regions at 24 h after surgery/sevoflurane. The apoptotic cells were detected by TUNEL (green), and the nuclei were detected by DAPI (blue). 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus 

Figure 7 | Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus 