Effect of Interaction between Early Menarche and Genetic Polymorphisms on Triglyceride
Table 1
Characteristics of study subjects.
Age at menarche (years)
All
b
≤12
13
14
15
16
≥17
Women, (%)
77 (2.4)
269 (8.5)
531 (16.6)
669 (21.1)
689 (21.7)
945 (29.8)
3180
Age at enrolment (years)
51.25 ± 6.92
52.58 ± 7.74
53.33 ± 8.47
54.92 ± 8.80
56.94 ± 8.82
59.18 ± 8.49
56.07 ± 8.88
<0.001
Area, (%)
Rural (Ansung)
26 (34)
83 (31)
199 (37)
339 (51)
412 (60)
640 (68)
1699
<0.001
Urban (Ansan)
51 (66)
186 (69)
332 (63)
330 (49)
277 (40)
305 (32)
1481
BMI (kg/m2)
25.55 ± 3.37
24.62 ± 3.42
24.78 ± 3.07
24.72 ± 3.20
24.86 ± 3.16
24.89 ± 3.12
24.80 ± 3.16
0.848
Current smokers, (%)
0 (0)
3 (1.1)
9 (1.7)
11 (1.6)
9 (1.3)
27 (2.9)
59 (1.8)
0.177
Alcohol consumption (g/l)
3.52 ± 11.18
1.51 ± 5.36
1.49 ± 5.28
1.40 ± 6.85
1.41 ± 6.16
1.28 ± 4.96
1.44 ± 5.96
0.068
Age at menopause
48.26 ± 3.83
47.52 ± 5.61
47.60 ± 4.62
47.87 ± 5.40
47.83 ± 5.11
47.90 ± 5.24
47.82 ± 5.16
0.718
OBS score
9.34 ± 2.41
9.39 ± 2.43
9.53 ± 2.56
9.19 ± 2.47
8.85 ± 2.53
8.91 ± 2.50
9.10 ± 2.51
0.698
CRP (mg/dl)
1.04 ± 1.34
1.22 ± 1.10
1.33 ± 1.24
1.35 ± 1.23
1.40 ± 1.27
1.53 ± 1.44
1.41 ± 1.30
0.07
Education, (%)
<0.001
Less than elementary school
7 (9.1)
20 (7.4)
55 (10.4)
95 (14.2)
138 (20.1)
225 (23.8)
540 (17)
Middle school graduate
24 (31.2)
111 (41.3)
185 (35)
305 (45.6)
384 (55.8)
575 (60.8)
1584 (50)
High school and above
46 (59.7)
138 (51.3)
289 (54.6)
269 (40.2)
166 (24.1)
141 (24.5)
1049 (33)
Income, (%)
<0.001
<100a
16 (20.8)
61 (22.7)
138 (26.4)
243 (36.6)
305 (44.8)
502 (53.1)
1265 (40.2)
100–200
23 (29.9)
59 (21.9)
112 (21.5)
144 (21.7)
156 (22.9)
220 (23.3)
714 (22.7)
≥200
38 (49.4)
149 (55.4)
272 (52.1)
277 (41.7)
220 (32.3)
214 (22.6)
1170 (37.1)
Values are expressed as means ± SDs (standard deviations) or number (%). BMI: body mass index; OBS: oxidative balance score; CRP: C-reactive protein; a104 KRW: equivalent with 1000 US dollar in 2014. b value was examined by the Kruskal-Wallis test or chi-square test.
