Research Article

NADPH Oxidase Isoforms Are Involved in Glucocorticoid-Induced Preosteoblast Apoptosis

Figure 5

NOX-derived ROS generation regulates the ASK1 and p38 phosphorylation in osteoblast apoptosis. (a) Representative immunoblots of p-ASK1, ASK1, p-p38, and p38 in osteoblast induced by 1000 nM DEX. (b) Representative densitometric analyses of p-ASK1/ASK1 and p-p38/p38. (c) RT-PCR detection of ASK1 mRNA in MC3T3-E1 cells. (d) RT-PCR detection of p38 mRNA in MC3T3-E1 cells (; ; ).
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