Increased Thioredoxin-1 Expression Promotes Cancer Progression and Predicts Poor Prognosis in Patients with Gastric Cancer

Table 1

Trx-1 expression and clinicopathological parameters in gastric cancer specimens.

	All cases	Trx-1 protein
	()	High expression	Low expression	value
Sex
Male	45	16	29
Female	99	50	49
Age (years)
<65	95	44	51
≥65	49	22	27
Clinical stage
I–II	79	43	36
III–IV	65	23	42
Differentiation grade
Well	1	0	1
Moderate	58	22	36
Poor	81	42	39
Missing	4	2	2
Tumor stage
N0/Ia	59	34	25
N1/Ib	26	14	12
N2/IIa	24	8	16
N3/IIb	35	10	25
Tumor size (cm)
<3.4	66	41	25
≥3.4	78	25	53

χ² test or Fisher’s exact test. Mann-Whitney test (nonparametric). All missing values were excluded during statistical analyses. , which was considered statistically significant.