Research Article

Influence of Age on Anticontractile Effect of Perivascular Adipose Tissue in Normotensive and Hypertensive Rats

Table 2

Characterization of adrenergic contractions in mesenteric arteries with perivascular adipose tissue removed (PVAT−) and intact (PVAT+), obtained from normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) at 5th and 12th week of life.

NATES
pEC50AUCAUC

WKY-5wPVAT−
PVAT+

WKY-12wPVAT−
PVAT+

SHR-5wPVAT−
PVAT+

SHR-12wPVAT−
PVAT+

NA: noradrenaline; TES: transmural electrical stimulation; pEC50: negative logarithm of half maximal effective noradrenaline concentration; AUC: area under curve. Values represent mean ± SEM of 10 rats. and PVAT+ vs. PVAT− in the respective experimental group of rats.